MMBR -- 73 (1): 1 Table 1

TABLE 1. Partial restoration of NO production by exogenous TNF- ${alpha}$ in cytochalasin B-inhibited macrophages treated with GBS and IFN

Treatment Nitrite production (nmol/sample)^a in macrophages treated with cytochalasin B at:

0 µg/ml 5 µg/ml 10 µg/ml

Medium only 0.03 ± 0.006 0.10 ± 0.03 0.06 ± 0.03

GBS + IFN 2.14 ± 0.49 0.10 ± 0.05^b 0.08 ± 0.05^b

TNF- ${alpha}$ + IFN 0.40 ± 0.13 0.42 ± 0.2 0.35 ± 0.02

TNF- ${alpha}$ + GBS + IFN 1.70 ± 0.6 0.49 ± 0.18^b 0.42 ± 0.10^b

^a Values are means ± standard deviations (four samples per group) for NO secreted by macrophages treated with GBS COH 1 (50 CFU per cell) and IFN (10 U/ml) or TNF- ${alpha}$ (1,000 U/ml).

^b Significantly different (P < 0.05) from value for non-cytochalasin-treated control group as calculated by Student's t test.