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Microbiol Mol Biol Rev. 1992 March; 56(1): 61-79

RNA recombination in animal and plant viruses.

M M Lai

Howard Hughes Medical Institute, University of Southern California, School of Medicine, Los Angeles 90033.

SUMMARY

An increasing number of animal and plant viruses have been shown to undergo RNA-RNA recombination, which is defined as the exchange of genetic information between nonsegmented RNAs. Only some of these viruses have been shown to undergo recombination in experimental infection of tissue culture, animals, and plants. However, a survey of viral RNA structure and sequences suggests that many RNA viruses were derived form homologous or nonhomologous recombination between viruses or between viruses and cellular genes during natural viral evolution. The high frequency and widespread nature of RNA recombination indicate that this phenomenon plays a more significant role in the biology of RNA viruses than was previously recognized. Three types of RNA recombination are defined: homologous recombination; aberrant homologous recombination, which results in sequence duplication, insertion, or deletion during recombination; and nonhomologous (illegitimate) recombination, which does not involve sequence homology. RNA recombination has been shown to occur by a copy choice mechanism in some viruses. A model for this recombination mechanism is presented.

Microbiol Mol Biol Rev. 1992 March; 56(1): 61-79




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  • Guillot, S., Caro, V., Cuervo, N., Korotkova, E., Combiescu, M., Persu, A., Aubert-Combiescu, A., Delpeyroux, F., Crainic, R. (2000). Natural Genetic Exchanges between Vaccine and Wild Poliovirus Strains in Humans. J. Virol. 74: 8434-8443 [Abstract] [Full Text]  
  • Riechmann, L., Winter, G. (2000). Novel folded protein domains generated by combinatorial shuffling of polypeptide segments. Proc. Natl. Acad. Sci. USA 10.1073/pnas.170145497v1 [Abstract] [Full Text]  
  • Varrelmann, M., Palkovics, L., Maiss, E. (2000). Transgenic or Plant Expression Vector-Mediated Recombination of Plum Pox Virus. J. Virol. 74: 7462-7469 [Abstract] [Full Text]  
  • Lai, M. M. C. (2000). The making of infectious viral RNA: No size limit in sight. Proc. Natl. Acad. Sci. USA 97: 5025-5027 [Full Text]  
  • Bruyere, A., Wantroba, M., Flasinski, S., Dzianott, A., Bujarski, J. J. (2000). Frequent Homologous Recombination Events between Molecules of One RNA Component in a Multipartite RNA Virus. J. Virol. 74: 4214-4219 [Abstract] [Full Text]  
  • Figlerowicz, M. (2000). Role of RNA structure in non-homologous recombination between genomic molecules of brome mosaic virus. Nucleic Acids Res 28: 1714-1723 [Abstract] [Full Text]  
  • Widjojoatmodjo, M. N., van Gennip, H. G. P., Bouma, A., van Rijn, P. A., Moormann, R. J. M. (2000). Classical Swine Fever Virus Erns Deletion Mutants: trans-Complementation and Potential Use as Nontransmissible, Modified, Live-Attenuated Marker Vaccines. J. Virol. 74: 2973-2980 [Abstract] [Full Text]  
  • Bodaghi, S., Ngon A Yassi, M., Dodds, J. A. (2000). Heterogeneity in the 3'-terminal untranslated region of tobacco mild green mosaic tobamoviruses from Nicotiana glauca resulting in variants with three or six pseudoknots. J. Gen. Virol. 81: 577-586 [Abstract] [Full Text]  
  • Gmyl, A. P., Belousov, E. V., Maslova, S. V., Khitrina, E. V., Chetverin, A. B., Agol, V. I. (1999). Nonreplicative RNA Recombination in Poliovirus. J. Virol. 73: 8958-8965 [Abstract] [Full Text]  
  • van Meerten, D., Zelwer, M., Regnier, P., Duin, J. (1999). In vivo oligo(A) insertions in phage MS2: role of Escherichia coli poly(A) polymerase. Nucleic Acids Res 27: 3891-3898 [Abstract] [Full Text]  
  • Worobey, M., Holmes, E. C. (1999). Evolutionary aspects of recombination in RNA viruses. J. Gen. Virol. 80: 2535-2543 [Full Text]  
  • Pierangeli, A., Bucci, M., Forzan, M., Pagnotti, P., Equestre, M., Pérez Bercoff, R. (1999). `Primer alignment-and-extension': a novel mechanism of viral RNA recombination responsible for the rescue of inactivated poliovirus cDNA clones. J. Gen. Virol. 80: 1889-1897 [Abstract] [Full Text]  
  • Ning, Q., Liu, M., Kongkham, P., Lai, M. M. C., Marsden, P. A., Tseng, J., Pereira, B., Belyavskyi, M., Leibowitz, J., Phillips, M. J., Levy, G. (1999). The Nucleocapsid Protein of Murine Hepatitis Virus Type 3 Induces Transcription of the Novel fgl2 Prothrombinase Gene. J. Biol. Chem. 274: 9930-9936 [Abstract] [Full Text]  
  • Raju, R., Hajjou, M., Hill, K. R., Botta, V., Botta, S. (1999). In Vivo Addition of Poly(A) Tail and AU-Rich Sequences to the 3' Terminus of the Sindbis Virus RNA Genome: a Novel 3'-End Repair Pathway. J. Virol. 73: 2410-2419 [Abstract] [Full Text]  
  • Sibold, C., Meisel, H., Kruger, D. H., Labuda, M., Lysy, J., Kozuch, O., Pejcoch, M., Vaheri, A., Plyusnin, A. (1999). Recombination in Tula Hantavirus Evolution: Analysis of Genetic Lineages from Slovakia. J. Virol. 73: 667-675 [Abstract] [Full Text]  
  • Figlerowicz, M., Nagy, P. D., Tang, N., Kao, C. C., Bujarski, J. J. (1998). Mutations in the N Terminus of the Brome Mosaic Virus Polymerase Affect Genetic RNA-RNA Recombination. J. Virol. 72: 9192-9200 [Abstract] [Full Text]  
  • Nishinaka, T., Shinohara, A., Ito, Y., Yokoyama, S., Shibata, T. (1998). Base pair switching by interconversion of sugar puckers in DNA extended by proteins of RecA-family: A model for homology search in homologous genetic recombination. Proc. Natl. Acad. Sci. USA 95: 11071-11076 [Abstract] [Full Text]  
  • Khromykh, A. A., Kenney, M. T., Westaway, E. G. (1998). trans-Complementation of Flavivirus RNA Polymerase Gene NS5 by Using Kunjin Virus Replicon-Expressing BHK Cells. J. Virol. 72: 7270-7279 [Abstract] [Full Text]  
  • Masuta, C., Ueda, S., Suzuki, M., Uyeda, I. (1998). Evolution of a quadripartite hybrid virus by interspecific exchange and recombination between replicase components of two related tripartite RNA viruses. Proc. Natl. Acad. Sci. USA 95: 10487-10492 [Abstract] [Full Text]  
  • Gal-On, A., Meiri, E., Raccah, B., Gaba, V. (1998). Recombination of Engineered Defective RNA Species Produces Infective Potyvirus In Planta. J. Virol. 72: 5268-5270 [Abstract] [Full Text]  
  • Meyers, G., Stoll, D., Gunn, M. (1998). Insertion of a Sequence Encoding Light Chain 3 of Microtubule-Associated Proteins 1A and 1B in a Pestivirus Genome: Connection with Virus Cytopathogenicity and Induction of Lethal Disease in Cattle. J. Virol. 72: 4139-4148 [Abstract] [Full Text]  
  • Herrewegh, A. A. P. M., Smeenk, I., Horzinek, M. C., Rottier, P. J. M., de Groot, R. J. (1998). Feline Coronavirus Type II Strains 79-1683 and 79-1146 Originate from a Double Recombination between Feline Coronavirus Type I and Canine Coronavirus. J. Virol. 72: 4508-4514 [Abstract] [Full Text]  
  • Nagy, P. D., Bujarski, J. J. (1998). Silencing Homologous RNA Recombination Hot Spots with GC-Rich Sequences in Brome Mosaic Virus. J. Virol. 72: 1122-1130 [Abstract] [Full Text]  
  • Nishinaka, T., Ito, Y., Yokoyama, S., Shibata, T. (1997). An extended DNA structure through deoxyribose-base stacking induced by RecA protein. Proc. Natl. Acad. Sci. USA 94: 6623-6628 [Abstract] [Full Text]  
  • Figlerowicz, M., Nagy, P. D., Bujarski, J. J. (1997). A mutation in the putative RNA polymerase gene inhibits nonhomologous, but not homologous, genetic recombination in an RNA virus. Proc. Natl. Acad. Sci. USA 94: 2073-2078 [Abstract] [Full Text]  
  • Falk, B., Bruening, G (1994). Will transgenic crops generate new viruses and new diseases?. Science 263: 1395-1396  
  • Greene, A., Allison, R. (1994). Recombination between viral RNA and transgenic plant transcripts. Science 263: 1423-1425 [Abstract]  
  • Cascone, P., Haydar, T., Simon, A. (1993). Sequences and structures required for recombination between virus-associated RNAs. Science 260: 801-805 [Abstract]  
  • Kim, M.-J., Kao, C. (2001). Factors regulating template switch in vitro by viral RNA-dependent RNA polymerases: Implications for RNA-RNA recombination. Proc. Natl. Acad. Sci. USA 98: 4972-4977 [Abstract] [Full Text]  
  • Riechmann, L., Winter, G. (2000). Novel folded protein domains generated by combinatorial shuffling of polypeptide segments. Proc. Natl. Acad. Sci. USA 97: 10068-10073 [Abstract] [Full Text]  


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