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Microbiol Mol Biol Rev, March 1998, p. 130-180, Vol. 62, No. 1
1092-2172/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Cell Wall and Secreted Proteins of Candida albicans: Identification, Function, and Expression

W. Lajean Chaffin,1 * José Luis López-Ribot,2 Manuel Casanova,3 Daniel Gozalbo,3 and José P. Martínez3

Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock,1 and Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio,2 Texas, and Departamento de Microbiología y Ecología, Facultad de Farmacia, Universitat de Valencia, Valencia, Spain3

The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida albicans. Although it was intially considered an almost inert cellular structure that protected the protoplast against osmotic offense, more recent studies have demonstrated that it is a dynamic organelle. The major components of the cell wall are glucan and chitin, which are associated with structural rigidity, and mannoproteins. The protein component, including both mannoprotein and nonmannoproteins, comprises some 40 or more moieties. Wall proteins may differ in their expression, secretion, or topological location within the wall structure. Proteins may be modified by glycosylation (primarily addition of mannose residues), phosphorylation, and ubiquitination. Among the secreted enzymes are those that are postulated to have substrates within the cell wall and those that find substrates in the extracellular environment. Cell wall proteins have been implicated in adhesion to host tissues and ligands. Fibrinogen, complement fragments, and several extracellular matrix components are among the host proteins bound by cell wall proteins. Proteins related to the hsp70 and hsp90 families of conserved stress proteins and some glycolytic enzyme proteins are also found in the cell wall, apparently as bona fide components. In addition, the expression of some proteins is associated with the morphological growth form of the fungus and may play a role in morphogenesis. Finally, surface mannoproteins are strong immunogens that trigger and modulate the host immune response during candidiasis.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430. Phone: (806) 743-2513. Fax: (806) 743-2334. E-mail: micwlc{at}ttuhsc.edu.

Microbiol Mol Biol Rev, March 1998, p. 130-180, Vol. 62, No. 1
1092-2172/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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  • Monteoliva, L., Lopez Matas, M., Gil, C., Nombela, C., Pla, J. (2002). Large-Scale Identification of Putative Exported Proteins in Candida albicans by Genetic Selection. Eukaryot Cell 1: 514-525 [Abstract] [Full Text]  
  • Cooke, V. M., Miles, R. J., Price, R. G., Midgley, G., Khamri, W., Richardson, A. C. (2002). New Chromogenic Agar Medium for the Identification of Candida spp.. Appl. Environ. Microbiol. 68: 3622-3627 [Abstract] [Full Text]  
  • Hogan, D. A., Kolter, R. (2002). Pseudomonas-Candida Interactions: An Ecological Role for Virulence Factors. Science 296: 2229-2232 [Abstract] [Full Text]  
  • Angiolella, L., Micocci, M. M., D'Alessio, S., Girolamo, A., Maras, B., Cassone, A. (2002). Identification of Major Glucan-Associated Cell Wall Proteins of Candida albicans and Their Role in Fluconazole Resistance. Antimicrob. Agents Chemother. 46: 1688-1694 [Abstract] [Full Text]  
  • Bacci, A., Montagnoli, C., Perruccio, K., Bozza, S., Gaziano, R., Pitzurra, L., Velardi, A., d'Ostiani, C. F., Cutler, J. E., Romani, L. (2002). Dendritic Cells Pulsed with Fungal RNA Induce Protective Immunity to Candida albicans in Hematopoietic Transplantation. J. Immunol. 168: 2904-2913 [Abstract] [Full Text]  
  • Nishikawa, A., Poster, J. B., Jigami, Y., Dean, N. (2002). Molecular and Phenotypic Analysis of CaVRG4, Encoding an Essential Golgi Apparatus GDP-Mannose Transporter. J. Bacteriol. 184: 29-42 [Abstract] [Full Text]  
  • Ramage, G., Vande Walle, K., Wickes, B. L., Lopez-Ribot, J. L. (2001). Standardized Method for In Vitro Antifungal Susceptibility Testing of Candida albicans Biofilms. Antimicrob. Agents Chemother. 45: 2475-2479 [Abstract] [Full Text]  
  • Ramage, G., Vande Walle, K., Wickes, B. L., Lopez-Ribot, J. L. (2001). Biofilm Formation by Candida dubliniensis. J. Clin. Microbiol. 39: 3234-3240 [Abstract] [Full Text]  
  • Weig, M., Haynes, K., Rogers, T. R., Kurzai, O., Frosch, M., Muhlschlegel, F. A. (2001). A GAS-like gene family in the pathogenic fungus Candida glabrata. Microbiology 147: 2007-2019 [Abstract] [Full Text]  
  • Jong, A. Y., Stins, M. F., Huang, S.-H., Chen, S. H. M., Kim, K. S. (2001). Traversal of Candida albicans across Human Blood-Brain Barrier In Vitro. Infect. Immun. 69: 4536-4544 [Abstract] [Full Text]  
  • Liu, L., Kang, K., Takahara, M., Cooper, K. D., Ghannoum, M. A. (2001). Hyphae and Yeasts of Candida albicans Differentially Regulate Interleukin-12 Production by Human Blood Monocytes: Inhibitory Role of C. albicans Germination. Infect. Immun. 69: 4695-4697 [Abstract] [Full Text]  
  • Alonso, R., Llopis, I., Flores, C., Murgui, A., Timoneda, J. (2001). Different adhesins for type IV collagen on Candida albicans: identification of a lectin-like adhesin recognizing the 7S(IV) domain. Microbiology 147: 1971-1981 [Abstract] [Full Text]  
  • Singleton, D. R., Masuoka, J., Hazen, K. C. (2001). Cloning and Analysis of a Candida albicans Gene That Affects Cell Surface Hydrophobicity. J. Bacteriol. 183: 3582-3588 [Abstract] [Full Text]  
  • Nisini, R., Romagnoli, G., Gomez, M. J., La Valle, R., Torosantucci, A., Mariotti, S., Teloni, R., Cassone, A. (2001). Antigenic Properties and Processing Requirements of 65-Kilodalton Mannoprotein, a Major Antigen Target of Anti-Candida Human T-Cell Response, as Disclosed by Specific Human T-Cell Clones. Infect. Immun. 69: 3728-3736 [Abstract] [Full Text]  
  • Glee, P. M., Cutler, J. E., Benson, E. E., Bargatze, R. F., Hazen, K. C. (2001). Inhibition of Hydrophobic Protein-Mediated Candida albicans Attachment to Endothelial Cells during Physiologic Shear Flow. Infect. Immun. 69: 2815-2820 [Abstract] [Full Text]  
  • Viudes, A., Perea, S., Lopez-Ribot, J. L. (2001). Identification of Continuous B-Cell Epitopes on the Protein Moiety of the 58-Kilodalton Cell Wall Mannoprotein of Candida albicans Belonging to a Family of Immunodominant Fungal Antigens. Infect. Immun. 69: 2909-2919 [Abstract] [Full Text]  
  • Smits, G. J., van den Ende, H., Klis, F. M. (2001). Differential regulation of cell wall biogenesis during growth and development in yeast. Microbiology 147: 781-794 [Full Text]  
  • Tzung, K.-W., Williams, R. M., Scherer, S., Federspiel, N., Jones, T., Hansen, N., Bivolarevic, V., Huizar, L., Komp, C., Surzycki, R., Tamse, R., Davis, R. W., Agabian, N. (2001). Genomic evidence for a complete sexual cycle in Candida albicans. Proc. Natl. Acad. Sci. USA 98: 3249-3253 [Abstract] [Full Text]  
  • Delgado, M. L., O’Connor, J. E., Azorín, I., Renau-Piqueras, J., Gil, M. L., Gozalbo, D. (2001). The glyceraldehyde-3-phosphate dehydrogenase polypeptides encoded by the Saccharomyces cerevisiae TDH1, TDH2 and TDH3 genes are also cell wall proteins. Microbiology 147: 411-417 [Abstract] [Full Text]  
  • Weber, Y., Santore, U. J., Ernst, J. F., Swoboda, R. K. (2001). Divergence of Eukaryotic Secretory Components: the Candida albicans Homolog of the Saccharomyces cerevisiae Sec20 Protein Is N Terminally Truncated, and Its Levels Determine Antifungal Drug Resistance and Growth. J. Bacteriol. 183: 46-54 [Abstract] [Full Text]  
  • La Valle, R., Sandini, S., Gomez, M. J., Mondello, F., Romagnoli, G., Nisini, R., Cassone, A. (2000). Generation of a Recombinant 65-Kilodalton Mannoprotein, a Major Antigen Target of Cell-Mediated Immune Response to Candida albicans. Infect. Immun. 68: 6777-6784 [Abstract] [Full Text]  
  • Maheshwari, R., Bharadwaj, G., Bhat, M. K. (2000). Thermophilic Fungi: Their Physiology and Enzymes. Microbiol. Mol. Biol. Rev. 64: 461-488 [Abstract] [Full Text]  
  • Chang, Y. C., Penoyer, L. A. (2000). Properties of Various RHO1 Mutant Alleles of Cryptococcus neoformans. J. Bacteriol. 182: 4987-4991 [Abstract] [Full Text]  
  • Braun, B. R., Head, W. S., Wang, M. X., Johnson, A. D. (2000). Identification and Characterization of TUP1-Regulated Genes in Candida albicans. Genetics 156: 31-44 [Abstract] [Full Text]  
  • Sturtevant, J. (2000). Applications of Differential-Display Reverse Transcription-PCR to Molecular Pathogenesis and Medical Mycology. Clin. Microbiol. Rev. 13: 408-427 [Abstract] [Full Text]  
  • Frisardi, M., Ghosh, S. K., Field, J., Van Dellen, K., Rogers, R., Robbins, P., Samuelson, J. (2000). The Most Abundant Glycoprotein of Amebic Cyst Walls (Jacob) Is a Lectin with Five Cys-Rich, Chitin-Binding Domains. Infect. Immun. 68: 4217-4224 [Abstract] [Full Text]  
  • Kirkpatrick, W. R., Lopez-Ribot, J. L., Mcatee, R. K., Patterson, T. F. (2000). Growth Competition between Candida dubliniensis and Candida albicans under Broth and Biofilm Growing Conditions. J. Clin. Microbiol. 38: 902-904 [Abstract] [Full Text]  
  • Davis, D., Wilson, R. B., Mitchell, A. P. (2000). RIM101-Dependent and -Independent Pathways Govern pH Responses in Candida albicans. Mol. Cell. Biol. 20: 971-978 [Abstract] [Full Text]  
  • Gaur, N. K., Klotz, S. A., Henderson, R. L. (1999). Overexpression of the Candida albicans ALA1 Gene in Saccharomyces cerevisiae Results in Aggregation following Attachment of Yeast Cells to Extracellular Matrix Proteins, Adherence Properties Similar to Those of Candida albicans. Infect. Immun. 67: 6040-6047 [Abstract] [Full Text]  
  • Lopez-Ribot, J. L., McAtee, R. K., Kirkpatrick, W. R., La Valle, R., Patterson, T. F. (1999). Low Levels of Antigenic Variability in Fluconazole-Susceptible and -Resistant Candida albicans Isolates from Human Immunodeficiency Virus-Infected Patients with Oropharyngeal Candidiasis. CVI 6: 665-670 [Abstract] [Full Text]  
  • Hoyer, L. L., Clevenger, J., Hecht, J. E., Ehrhart, E. J., Poulet, F. M. (1999). Detection of Als Proteins on the Cell Wall of Candida albicans in Murine Tissues. Infect. Immun. 67: 4251-4255 [Abstract] [Full Text]  
  • Calera, J. A., Zhao, X.-J., De Bernardis, F., Sheridan, M., Calderone, R. (1999). Avirulence of Candida albicans CaHK1 Mutants in a Murine Model of Hematogenously Disseminated Candidiasis. Infect. Immun. 67: 4280-4284 [Abstract] [Full Text]  
  • Cannon, R.D., Chaffin, W.L. (1999). Oral Colonization By Candida Albicans. CROBM 10: 359-383 [Abstract] [Full Text]  
  • Hoyer, L. L., Payne, T. L., Hecht, J. E. (1998). Identification of Candida albicans ALS2 and ALS4 and Localization of Als Proteins to the Fungal Cell Surface. J. Bacteriol. 180: 5334-5343 [Abstract] [Full Text]  
  • Gozalbo, D., Gil-Navarro, I., Azorin, I., Renau-Piqueras, J., Martinez, J. P., Gil, M. L. (1998). The Cell Wall-Associated Glyceraldehyde-3-Phosphate Dehydrogenase of Candida albicans Is Also a Fibronectin and Laminin Binding Protein. Infect. Immun. 66: 2052-2059 [Abstract] [Full Text]  


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