This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rice, K. C.
Right arrow Articles by Bayles, K. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rice, K. C.
Right arrow Articles by Bayles, K. W.

 Previous Article  |  Next Article 

Microbiology and Molecular Biology Reviews, March 2008, p. 85-109, Vol. 72, No. 1
1092-2172/08/$08.00+0     doi:10.1128/MMBR.00030-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Molecular Control of Bacterial Death and Lysis

Kelly C. Rice and Kenneth W. Bayles*

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-6245

Summary: Although the phenomenon of bacterial cell death and lysis has been studied for over 100 years, the contribution of these important processes to bacterial physiology and development has only recently been recognized. Contemporary study of cell death and lysis in a number of different bacteria has revealed that these processes, once thought of as being passive and unregulated, are actually governed by highly complex regulatory systems. An emerging paradigm in this field suggests that, analogous to programmed cell death in eukaryotes, regulated cell death and lysis in bacteria play an important role in both developmental processes, such as competence and biofilm development, and the elimination of damaged cells, such as those irreversibly injured by environmental or antibiotic stress. Further study in this exciting field of bacterial research may provide new insight into the potential evolutionary link between control of cell death in bacteria and programmed cell death (apoptosis) in eukaryotes.

* Corresponding author. Mailing address: Department of Microbiology and Pathology, University of Nebraska Medical Center, 668 S. 41st St., PYH4014, Omaha, NE 68198-6245. Phone: (402) 559-4945. Fax: (402) 559-4077. E-mail: kbayles{at}unmc.edu

Microbiology and Molecular Biology Reviews, March 2008, p. 85-109, Vol. 72, No. 1
1092-2172/08/$08.00+0     doi:10.1128/MMBR.00030-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kreth, J., Vu, H., Zhang, Y., Herzberg, M. C. (2009). Characterization of Hydrogen Peroxide-Induced DNA Release by Streptococcus sanguinis and Streptococcus gordonii. J. Bacteriol. 191: 6281-6291 [Abstract] [Full Text]  
  • Uehara, T., Dinh, T., Bernhardt, T. G. (2009). LytM-Domain Factors Are Required for Daughter Cell Separation and Rapid Ampicillin-Induced Lysis in Escherichia coli. J. Bacteriol. 191: 5094-5107 [Abstract] [Full Text]  
  • Sharma-Kuinkel, B. K., Mann, E. E., Ahn, J.-S., Kuechenmeister, L. J., Dunman, P. M., Bayles, K. W. (2009). The Staphylococcus aureus LytSR Two-Component Regulatory System Affects Biofilm Formation. J. Bacteriol. 191: 4767-4775 [Abstract] [Full Text]  
  • Wormser, G. P., Schwartz, I. (2009). Antibiotic Treatment of Animals Infected with Borrelia burgdorferi. Clin. Microbiol. Rev. 22: 387-395 [Abstract] [Full Text]  
  • Chandramohan, L., Ahn, J.-S., Weaver, K. E., Bayles, K. W. (2009). An Overlap between the Control of Programmed Cell Death in Bacillus anthracis and Sporulation. J. Bacteriol. 191: 4103-4110 [Abstract] [Full Text]  
  • Karatan, E., Watnick, P. (2009). Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms. Microbiol. Mol. Biol. Rev. 73: 310-347 [Abstract] [Full Text]  
  • Harrison, J. J., Wade, W. D., Akierman, S., Vacchi-Suzzi, C., Stremick, C. A., Turner, R. J., Ceri, H. (2009). The Chromosomal Toxin Gene yafQ Is a Determinant of Multidrug Tolerance for Escherichia coli Growing in a Biofilm. Antimicrob. Agents Chemother. 53: 2253-2258 [Abstract] [Full Text]  
  • Nichols, J. R., Aldrich, A. L., Mariani, M. M., Vidlak, D., Esen, N., Kielian, T. (2009). TLR2 Deficiency Leads to Increased Th17 Infiltrates in Experimental Brain Abscesses. J. Immunol. 182: 7119-7130 [Abstract] [Full Text]  
  • Mann, E., Zaunbrecher, M. A, Hitz, K., Churchward, G. (2008). The 52nd Annual Wind River Conference on Prokaryotic Biology--2008. J. Bacteriol. 190: 7871-7875 [Full Text]  
  • Haddix, P. L., Jones, S., Patel, P., Burnham, S., Knights, K., Powell, J. N., LaForm, A. (2008). Kinetic Analysis of Growth Rate, ATP, and Pigmentation Suggests an Energy-Spilling Function for the Pigment Prodigiosin of Serratia marcescens. J. Bacteriol. 190: 7453-7463 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»