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TABLE 1. World Wide Web tools for searching databases with protein information obtained either from mass spectrometry or from Edman degradation

Site name URL Information available Reference MOWSE http://srs.hgmp.mrc.ac.uk/cgi-bin/mowse Peptide mass mapping and sequencing 125 ProFound http://prowl.rockefeller.edu/cgi-bin/ProFound Peptide mass mapping and sequencing 176 PeptIdent http://www.expasy.ch/tools/peptident. Peptide mass mapping and sequencing 165 PepSea http://195.41.108.38/PepSeaIntro.html Peptide mass mapping and sequencing 102 MASCOT http://www.matrixscience.com/ Peptide mass mapping and sequencing 129 PepFrag http://www.proteometrics.com/ Peptide mass mapping and sequencing 54 Protein Prospector http://prospector.ucsf.edu/ Peptide mass mapping and sequencing 32 FindMod http://www.expasy.ch/tools/findmod/ Posttranslational modification 166 SEAQUEST http://fields.scripps.edu/sequest/ Uninterpreted MS/MS searching 49 FASTA Search Programs http://fasta.bioch.virginia.edu/ Protein and nucleotide database searching 101 Cleaved Radioactivity of Phosphopeptides http://fasta.bioch.virginia.edu/crp Protein phosphorylation site mapping MacDonald et al. submitted

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