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Review

Emerging Roles of Functional Bacterial Amyloids in Gene Regulation, Toxicity, and Immunomodulation

Nir Salinas, Tatyana L. Povolotsky, Meytal Landau, Ilana Kolodkin-Gal
Nir Salinas
aDepartment of Biology, Technion–Israel Institute of Technology, Haifa, Israel
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Tatyana L. Povolotsky
bDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
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Meytal Landau
aDepartment of Biology, Technion–Israel Institute of Technology, Haifa, Israel
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Ilana Kolodkin-Gal
bDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
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  • ORCID record for Ilana Kolodkin-Gal
DOI: 10.1128/MMBR.00062-20
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Emerging Roles of Functional Bacterial Amyloids in Gene Regulation, Toxicity, and Immunomodulation
Nir Salinas, Tatyana L. Povolotsky, Meytal Landau, Ilana Kolodkin-Gal
Microbiology and Molecular Biology Reviews Nov 2020, 85 (1) e00062-20; DOI: 10.1128/MMBR.00062-20

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Emerging Roles of Functional Bacterial Amyloids in Gene Regulation, Toxicity, and Immunomodulation
Nir Salinas, Tatyana L. Povolotsky, Meytal Landau, Ilana Kolodkin-Gal
Microbiology and Molecular Biology Reviews Nov 2020, 85 (1) e00062-20; DOI: 10.1128/MMBR.00062-20
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  • Article
    • SUMMARY
    • INTRODUCTION
    • FUNCTIONAL AMYLOIDS IN COLONY STRUCTURE
    • THE FUNCTIONAL AMYLOID TasA OF B. SUBTILIS AS A REGULATOR OF CELL FATE
    • STRUCTURAL POLYMORPHISM ENCODE DIFFERENT ACTIVITIES OF THE S. AUREUS PSM FUNCTIONAL AMYLOIDS
    • THE SCAFFOLD AMYLOID CURLI SERVES AS AN IMMUNOMODULATOR
    • CONCLUSIONS AND FUTURE DIRECTIONS: TARGETING FUNCTIONAL AMYLOIDS TO CONTROL MULTICELLULAR MICROBIAL COMMUNITIES
    • ACKNOWLEDGMENTS
    • REFERENCES
    • Author Bios
  • Figures & Data
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  • PDF

KEYWORDS

amyloids
Bacillus subtilis
biofilms
curli
phenol-soluble modulins
Staphylococcus aureus
Escherichia coli
Salmonella enterica serovar Typhimurium
TasA
extracellular matrix

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