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Review

More than a Pore: Nonlytic Antimicrobial Functions of Complement and Bacterial Strategies for Evasion

Elisabet Bjanes, Victor Nizet
Elisabet Bjanes
aDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, California, USA
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Victor Nizet
aDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, California, USA
bSkaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, California, USA
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DOI: 10.1128/MMBR.00177-20
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Article Information

DOI 
https://doi.org/10.1128/MMBR.00177-20
PubMed 
33504655

Published By 
American Society for Microbiology Journals
History 
  • Published online January 27, 2021.

Copyright & Usage 
Copyright © 2021 American Society for Microbiology. All Rights Reserved.

Author Information

  1. Elisabet Bjanesa and
  2. Victor Nizeta,b
  1. aDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, California, USA
  2. bSkaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, California, USA
  • Address correspondence to Elisabet Bjanes, ebjanes{at}health.ucsd.edu, or Victor Nizet, vnizet{at}health.ucsd.edu.
  • Citation Bjanes E, Nizet V. 2021. More than a pore: nonlytic antimicrobial functions of complement and bacterial strategies for evasion. Microbiol Mol Biol Rev 85:e00177-20. https://doi.org/10.1128/MMBR.00177-20.

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More than a Pore: Nonlytic Antimicrobial Functions of Complement and Bacterial Strategies for Evasion
Elisabet Bjanes, Victor Nizet
Microbiology and Molecular Biology Reviews Jan 2021, 85 (1) e00177-20; DOI: 10.1128/MMBR.00177-20

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More than a Pore: Nonlytic Antimicrobial Functions of Complement and Bacterial Strategies for Evasion
Elisabet Bjanes, Victor Nizet
Microbiology and Molecular Biology Reviews Jan 2021, 85 (1) e00177-20; DOI: 10.1128/MMBR.00177-20
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    • SUMMARY
    • INTRODUCTION
    • BY THE BOOK: CANONICAL COMPLEMENT CASCADES
    • NONLYTIC COMPLEMENT FUNCTIONS AND BACTERIAL EVASION MECHANISMS
    • REFRAMING SCIENTIFIC PARADIGMS AND THERAPEUTIC APPROACHES TO ENCOMPASS COMPLEMENT
    • CONCLUSIONS
    • REFERENCES
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KEYWORDS

autophagy
bacterial pathogenesis
complement
innate immunity
macrophages
neutrophils
opsonization
phagocytosis
virulence factors

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