Table 3.

TAF subunits of yeast TFIID

FactorMass (kDa)Gene(s)EssentialCharacteristicsMetazoan homolog(s)Reference(s)
TAFII150155 TSM1 YesdTAFII150 371, 385
TAFII145/TAFII130121 TAF130 YesScaffold for assembly of TFIID; directly contacts TBPhTAFII250 (CCG1), dTAFII230 371, 385
TAFII9089 TAF90 YesdTAFII80 binds TFIIEα and TFIIFαhTAFII100, dTAFII80 371, 388
TAFII6767 TAF67 YeshTAFII55 329
TAFII61/TAFII6861 TAF61 YesStructural similarity to histone H2BhTAFII15/20, dTAFII30α (p28/p22) 329, 517
TAFII6058 TAF60 YesStructural similarity to histone H4hTAFII80, dTAFII60 371
TAFII4740 TAF47 YesNone517
TAFII4041 TAF40 YesdTAFII40 binds TFIIBhTAFII28, dTAFII30β 255, 329
TAFII3027 TAF30, ANC1,TFG3, SWP29 NoSubunit common to TFIID, TFIIF, and the SWI/SNF complexAF-9, ENL 55, 196, 531
TAFII23/TAFII2523 TAF25 YeshTAFII30 256, 329
TAFII1919 TAF19,FUN81 hTAFII18 329
TAFII1717 TAF17 YesStructural similarity to histone H3hTAFII32, dTAFII40/42 329