Table 3.

TAF subunits of yeast TFIID

FactorMass (kDa)Gene(s)EssentialCharacteristicsMetazoan homolog(s)Reference(s)
TAFII150155TSM1YesdTAFII150371, 385
TAFII145/TAFII130121TAF130YesScaffold for assembly of TFIID; directly contacts TBPhTAFII250 (CCG1), dTAFII230371, 385
TAFII9089TAF90YesdTAFII80 binds TFIIEα and TFIIFαhTAFII100, dTAFII80371, 388
TAFII6767TAF67YeshTAFII55329
TAFII61/TAFII6861TAF61YesStructural similarity to histone H2BhTAFII15/20, dTAFII30α (p28/p22)329, 517
TAFII6058TAF60YesStructural similarity to histone H4hTAFII80, dTAFII60371
TAFII4740TAF47YesNone517
TAFII4041TAF40YesdTAFII40 binds TFIIBhTAFII28, dTAFII30β255, 329
TAFII3027TAF30, ANC1,TFG3, SWP29NoSubunit common to TFIID, TFIIF, and the SWI/SNF complexAF-9, ENL55, 196, 531
TAFII23/TAFII2523TAF25YeshTAFII30256, 329
TAFII1919TAF19,FUN81hTAFII18329
TAFII1717TAF17YesStructural similarity to histone H3hTAFII32, dTAFII40/42329