Table 1.

Code, accession number, class, and size for multimodular PBPs

SourceaPBP codeData bankbAccession no.SubclasscResidue no.
Gram-positive bacteria
+ Bacillus subtilis Bsu1S P39793 A3914
Bsu2cS P38050 A4714
Bsu4S P40750 A5624
Bsu3S P42971 B1668
BsuVDS Q03524 B3645
Bsu2bS Q07868 B4716
Bsu2aS P54488 B5716
Enterococcus faecalis Efas5E X78425 B1679
Enterococcus faecium Efam5E X84859 B1673
EfamCE U94707 B4742
Enterococcus hirae Ehi3rP A36903 B1678
Ehi5E X62280 B1678
Ehi3sE Y13922 B4730
Staphylococcus aureus Sau2P S43693 A3716
SauBE U94706 B4646
Staphylococcus sciuri Ssc2E Y09223 B1666
Streptococcus oralis Sor1aS Q00573 A3637
Streptococcus pneumoniae Spn1aS Q04707 A3719
Spn2aE AJ002292 A4731
Spn1bE AJ002291 A5821
Spn2xS P14677 B4750
Spn2bS P10524 B5679
Streptococcus pyogenes Spy263Ocontig 263A3721
Spy250Ocontig 250A4778
Spy286Ocontig 286A5723
Spy290Ocontig 290B4752
Streptococcus thermophilus Sth2bE U58210 B5704
Mycobacterium leprae Mle1* E L39923 A686
Mle1E L01263 A821
Mycobacterium tuberculosis Mtu1E Z80775 A665
Streptomyces clavuligerus SclpcbrE U56256 A:B551
Streptomyces coelicolor Scoa3E Y14206 B:B2770
Gram-negative bacteria
Citrobacter freundii Cfr1bP S57580 A2846
+ Escherichia coli Eco1aS P02918 A1850
Eco1bS P02919 A2844
Eco1cE U88571 A770
Eco2S P08150 B2633
Eco3S P04286 B3588
+ Haemophilus influenzae Hin1aS P31776 A1853
Hin1bS P45345 A2781
Hin2P C64044 B2651
Hin3P G64184 B3610
Neisseria gonorrhoeae Ngo1E U72876 A1798
Ngo2P S49090 B3582
Neisseria meningitidis Nme1E U80933 A1798
Nme2E X59624 B3584
Pseudomonas aeruginosa Pae1aE U73780 A1822
Pae3P S54872 B3579
Pae3aE X95517 B3565
Spiral-shaped and filamentous gram-negative related bacteria
+ Helicobacter pylori Hpy1aE AE000573 A2659
Hpy2E AE000654 B:B2588
+ Borrelia burgdorferi Bbu3G AE001173 A1932
Bbu2G AE001171 B:B2599
Bbu1G AE001125 B3629
+ Aquifex aeolicus AaemrcaG AE000699 A1726
AaeA1G AE000728 B2595
AaeA2G AE000695 B3578
+ Synechocystis strain PCC6803Syn1aKsll0002A1885
  • a + denotes that the genome has been sequenced.

  • b E, EMBL DNA data bank; G, GenBank; K, Kazusa DNA Research Institute data bank at http://www.kazusa.or.jap; O, Oklahoma University DNA data bank at; P, PIR data bank; S, Swiss-Prot data bank; T, TIGR Microbial data bank at

  • c Letters without suffixes indicate that the PBP does not belong to a defined subclass. A:B indicates that the n-PB and PB modules of the PBP are of classes A and B, respectively. B:B2 and B:B3 indicate that the n-PB module of the PBP is an outlier of class B.