Table 1.

Code, accession number, class, and size for multimodular PBPs

SourceaPBP codeData bankbAccession no.SubclasscResidue no.
Gram-positive bacteria
+Bacillus subtilisBsu1SP39793A3914
Bsu2cSP38050A4714
Bsu4SP40750A5624
Bsu3SP42971B1668
BsuVDSQ03524B3645
Bsu2bSQ07868B4716
Bsu2aSP54488B5716
Enterococcus faecalisEfas5EX78425B1679
Enterococcus faeciumEfam5EX84859B1673
EfamCEU94707B4742
Enterococcus hiraeEhi3rPA36903B1678
Ehi5EX62280B1678
Ehi3sEY13922B4730
Staphylococcus aureusSau2PS43693A3716
Sau2aPJQ0773B1668
SauBEU94706B4646
Staphylococcus sciuriSsc2EY09223B1666
Streptococcus oralisSor1aSQ00573A3637
Streptococcus pneumoniaeSpn1aSQ04707A3719
Spn2aEAJ002292A4731
Spn1bEAJ002291A5821
Spn2xSP14677B4750
Spn2bSP10524B5679
Streptococcus pyogenesSpy263Ocontig 263A3721
Spy250Ocontig 250A4778
Spy286Ocontig 286A5723
Spy290Ocontig 290B4752
Streptococcus thermophilusSth2bEU58210B5704
Actinomycetales
Mycobacterium lepraeMle1*EL39923A686
Mle1EL01263A821
Mycobacterium tuberculosisMtu1EZ80775A665
Streptomyces clavuligerusSclpcbrEU56256A:B551
Streptomyces coelicolorScoa3EY14206B:B2770
Gram-negative bacteria
Citrobacter freundiiCfr1bPS57580A2846
+Escherichia coliEco1aSP02918A1850
Eco1bSP02919A2844
Eco1cEU88571A770
Eco2SP08150B2633
Eco3SP04286B3588
+Haemophilus influenzaeHin1aSP31776A1853
Hin1bSP45345A2781
Hin2PC64044B2651
Hin3PG64184B3610
Neisseria gonorrhoeaeNgo1EU72876A1798
Ngo2PS49090B3582
Neisseria meningitidisNme1EU80933A1798
Nme2EX59624B3584
Pseudomonas aeruginosaPae1aEU73780A1822
Pae3PS54872B3579
Pae3aEX95517B3565
Spiral-shaped and filamentous gram-negative related bacteria
+Helicobacter pyloriHpy1aEAE000573A2659
Hpy2EAE000654B:B2588
Hpy3THP1556B:B3615
+Borrelia burgdorferiBbu3GAE001173A1932
Bbu2GAE001171B:B2599
Bbu1GAE001125B3629
+Aquifex aeolicusAaemrcaGAE000699A1726
AaeA1GAE000728B2595
AaeA2GAE000695B3578
Cyanobacteria
+Synechocystis strain PCC6803Syn1aKsll0002A1885
SynmrcaKsll1434A1650
SynmrcbKslr1710A1749
Syn3Ksll1833B3607
  • a + denotes that the genome has been sequenced.

  • b E, EMBL DNA data bank; G, GenBank; K, Kazusa DNA Research Institute data bank at http://www.kazusa.or.jap ; O, Oklahoma University DNA data bank at http://www.genome.ou.edu ; P, PIR data bank; S, Swiss-Prot data bank; T, TIGR Microbial data bank athttp://www.tigr.org .

  • c Letters without suffixes indicate that the PBP does not belong to a defined subclass. A:B indicates that the n-PB and PB modules of the PBP are of classes A and B, respectively. B:B2 and B:B3 indicate that the n-PB module of the PBP is an outlier of class B.