TABLE 5.

Corresponding regulators in the fission yeast Sty1 and the budding yeast HOG pathways

Budding yeast proteinFission yeast homologFunction% Identity/ % similarityReference(s)
Hog1pSty1/Spc1/Phh1MAP kinase82/91 278, 384, 548
Pbs2pWis1MAPKK44/58 639
Ssk2p and Ssk22pWis4/Wik1/Wak1 and Win1MAPKKK30/50 162, 522, 523, 553, 639
Ssk1pMcs4Response regulator42/58 107, 545, 553
Ypd1pMpr1/Spy1/Sph1Phosphorelay protein48/75 21, 416
Ptp2pPyp1Phosphotyrosine phosphatase27/41 385, 443
Ptp3pPyp2Phosphotyrosine phosphatase21/37 385, 443
Ptc1pPtc1Phosphothreonine phosphatase46/66 549
Ptc2pPtc3Phosphothreonine phosphatase50/68 549
Ptc3pPtc2Phosphothreonine phosphatase48/65 549
Yap1pPap1Transcriptional activator, oxidative stress26/41 600, 601
Sko1/Acr1pAtf1Transcriptional regulator, osmotic stress25/37 550, 586, 647
Skn7pPrr1Response regulator, transcriptional regulator32/49 434