Table 2.

Relationship between natural salivary IgA antibodies to mutans streptococci and caries experience

No. of subjects in study group (age [yr])SampleAntigens of mutans streptococci in immunoassay (serotype)Correlation of salivary IgA antibodies with DMFSaProtection against cariesReference
17 (2.5–5.5)Whole salivaWhole cells (b, c)Yes 134
289 (military recruits)Whole salivaWhole cells (c, g)Yes 265
42 (22–39)Whole and parotid salivaWhole cells (c), antigen I/II, carbohydrate (c)Yes 72
64 (3–6)Whole salivaWhole cells (c, d), antigen I/II, carbohydrate (c, d)Yes 71
131 (17–44)Parotid salivaWhole cells (c), purified antigensYes 171
41 (7–11)Whole and parotid salivaWhole cells (c)Yes 402
40 (dental school students)Whole and parotid salivaWhole cells (c), antigensYes 173
96 (18–24)Parotid salivaWhole cells (c)+No 75
100 (20–30)Whole salivaWhole cells (a, c, d)NoNo 135
63 (6–13)Whole salivaWhole cells (b–g)NoNo 390
50 (19–21)Whole salivaWhole cells (c)NoNo 169
67 (4–9)Whole salivaWhole cells (c)NoNo 1
59 (22–32)Whole salivaWhole cells (c)NoNo 491
43 (20–64)Whole salivaWhole cells (g), antigen I/II, carbohydrate (g)NoNo 195
  • a Negative (−), positive (+), or no correlation.