Table 4.

Relationship between natural salivary IgA antibodies to mutans streptococci and the level of mutans streptococci

No. of subjects in study group (age [yr])SampleAntigens of mutans streptococci for immunoassay (serotype)Correlation of salivary IgA antibodies with the level of mutans streptococciaReference
? (children)Whole salivaGlucosyltransferase, antigen I/II, glucan-binding protein, 110-kDa antigen 453
 10 (22–59)Mouth rinsesWhole cells (c, d)b 246
 12 (27–43)Parotid salivaCarbohydrate (a–g)b 177
 20 (young adults)Mouth rinsesWhole cells (c)b 357
 55 (18–20)Parotid salivaWhole cells (c, d)+ 202
19 (adults)Whole salivaWhole cells (c)+ 266
 21 (0.3–35)Whole salivaGlucosyltransferase, antigen I/II, glucan binding protein+ 451
 12 (0.5–44)Whole salivaWhole cellsNo 24
 42 (22–39)Whole and parotid salivaWhole cells (c), antigen I/II, carbohydrate (c)No 72
 64 (3–6)Whole salivaWhole cells (c, d), antigen I/II, carbohydrate (c, d)No 71
 31 (0.8–3.8)Whole salivaWhole cells (c)No 492
 50 (19–21)Whole salivaWhole cells (c)No 169
 67 (4–9)Whole salivaWhole cells (c)No 1  
 59 (22–32)Whole salivaWhole cells (c)No 491
  • a Negative (−), positive (+), or no correlation.

  • b Negative correlation with implanted mutans streptococci.