Table 2.

Type I R-M systems identified in members of the family Enterobacteriaceae

R-M familyEnzymeTarget sequenceReference(s)
IAEcoKIaAAC(N6)GTGC79
EcoBIbTGA(N8)TGCT147
EcoDITTA(N7)GTCY125
StyLTIIIcGAG(N6)RTAYG126
StySPIAAC(N6)GTRC126
EcoR5INDd11
EcoR10IeND11
EcoR23IND11
IBEcoAIGAG(N7)GTCA91, 168
EcoEIGAG(N7)ATGC33
CfrAIGCA(N8)GTGG80
StySKICGAT(N7)GTTA179
StySTIND10
EcoR17IND11
EcoR42IND11
ICEcoR124IGAA(N6)RTCG142
EcoDXXITCA(N7)RTTC64
EcoprrICCA(N7)RTGC183
IDStySBLICGA(N6)TACC180; Titheradge and Murray, unpublished
EcoR9IND11
KpnAIND101
  • a Strains ECOR12 and -24 have type IA systems with the same specificity.

  • b Strains ECOR14, 42 and 70 have type IA systems with the same specificity.

  • c Referred to as StySBI in the early literature.

  • d ND, not done.

  • e Strain ECOR25 has a type IA system with the same specificity.