Table 1.

Historical perspective on the mineralization of aromatic compounds by E. coli

YrAuthor(s) and locationEventa
1980R. A. Cooper and M. A. Skinner (Leicester) First report on a pathway for the catabolism of aromatic acids in E. coli(mineralization of 3HPA and 4HPA)
1983R. P. Burlingame and P. J. Chapman (Minnesota) E. colimineralizes a variety of aromatic acids (PA, HPA, PP, 3HPP, 3HCI); biochemical characterization of the PP and 3HPP catabolic pathway.
1985R. A. Cooper, D. C. Jones, and S. Parrot (Leicester)Isolation of the first E. colimutants defective in catabolism of aromatic acids (PAmutants)
1986R. P. Burlingame, L. Wyman, and P. J. Chapman (Minnesota)Isolation and characterization ofE. coli mutants defective in PP and 3HPP degradation
1987S. Parrot, S. Jones, and R. A. Cooper (Leicester)First report on the catabolism of aromatic amines in E. coli (PEA can be used as nitrogen and carbon source)
1987N. Abdulrashid and D. P. Clark (Illinois)Degradation of furans and thiophenes byE. coli mutants
1988J. R. Jenkins and R. A. Cooper (Leicester)Molecular cloning of themeta cleavage route (hpc genes) involved in HPC degradation
1990D. I. Roper and R. A. Cooper (Leicester)First nucleotide sequence of a gene (hpcD) involved in mineralization of aromatic compounds (HPA) in E. coli
1993D. I. Roper, T. Fawcett, and R. A. Cooper (Leicester)First nucleotide sequence of a regulatory gene (hpcR) that controls the expression of an aromatic catabolic operon (hpc) in E. coli
1994M. A. Prieto and J. L. Garcı́a (Madrid)Characterization of the HpaBC monooxygenase fromE. coli; first primary structure of a TC-FDM
1996M. A. Prieto, E. Dı́az, and J. L. Garcı́a (Madrid)Molecular characterization of a complete aromatic catabolic pathway from E. coli(hpa cluster) and its use to construct a mobile degradative cassette; expansion of the degradative abilities of P. putida by expressing some hpa genes
1997M. A. Prieto and J. L. Garcı́a (Madrid)Characterization of the first gene (hpaX) responsible of the transport of an aromatic acid (HPA) in E. coli
1997A. Ferrández, J. L. Garcı́a, and E. Dı́az (Madrid)Heterologous expression of a complete aromatic catabolic pathway (mhp) from E. coli to improve the catabolic abilities of different environmentally relevant bacteria
1998E. Dı́az, A. Ferrández, and J. L. Garcı́a (Madrid)Molecular characterization of the hcacluster encoding a multicomponent aromatic initial dioxygenase inE. coli
1998A. Ferrández, B. Miñambres, B. Garcı́a, E. R. Olivera, J. M. Luengo, J. L. Garcı́a, and E. Dı́az (Madrid)Molecular characterization of an aerobic hybrid pathway for the catabolism of PA in E. coli
  • a Abbreviations: HPA, hydroxyphenylacetic acid; HPC, homoprotocatechuate; 3HPP, 3-hydroxyphenylpropionic acid; 3HCI, 3-hydroxycinnamic acid; PA, phenylacetic acid; PEA, 2-phenylethylamine; PP, phenylpropionic acid; TC-FDM, two-component nonheme flavin-diffusible monooxygenase.