Table 4.

Enzymatic reactions on aromatic compounds other than those involved in their mineralization

GeneaLocation (min)bGene productSize (aa)SubstratePathway
tnaA 83.8 l-Tryptophanase471 l-TryptophanTryptophan catabolism
ubiD(yigC)86.7Hydroxybenzoate decarboxylase4973-Octaprenyl-4-hydroxybenzoateUbiquinone biosynthesis
ubiX(dedF)52.3Decarboxylase1893-Octaprenyl-4-hydroxybenzoate,p- and o-aminobenzoate?Ubiquinone biosynthesis?
ubiE 86.7Methyltransferase2512-Octaprenyl-6-methoxy-1,4-benzoquinolUbiquinone biosynthesis
ubiG 50.3Methyltransferase2402-Octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinolUbiquinone biosynthesis
ubiB (yigR)86.7Putative kinase involved in hydroxylation reaction5462-Octaprenylphenol?Ubiquinone biosynthesis
ubiH (visB)65.7Monocomponent flavin-type monooxygenase3922-Octaprenyl-6-methoxyphenolUbiquinone biosynthesis
ubiF(yleB)14.9Monocomponent flavin-type monooxygenase3912-Octaprenyl-3-methyl-6-methoxy-1,4-benzoquinolUbiquinone biosynthesis
entA 13.4Dihydrodiol dehydrogenase248 trans-2,3-Dihydro-2,3-dihydroxybenzoateEnterobactin biosynthesis
entE 13.4AMP ligase5362,3-DihydroxybenzoateEnterobactin biosynthesis
menE 51.1CoA Ligase451 o-Succinylbenzoic acidMenaquinone biosynthesis
nfsA(nfnA)19.2Nitroreductase IA240Nitroaromatics (nitrofurazone, nitrobenzoate, nitrophenol, nitrotoluene, etc.) and azo dyes.Defense against oxidative stress?
nfsB(nfnB)13.0Nitroreductase IB1 (pteridine reductase)217Recycling pterin cofactors
nhoA 33.0Putative arylamineN-acetyltransferase2812-Aminofluorene,p-aminobenzoateDetoxification?
aslA 85.8551
ydeN 34.0Putative arylsulfatases571Aryl sulfatesd Catabolism of arylsulfates?
yidJ 83.0497
pacc 98.8Penicillin G acylase846Esters and amides of PA and HPACatabolism of natural esters and amides of PA and HPA ?
  • a Additional gene designations are indicated in parentheses.

  • b The location of the genes is with respect to the E. coli K-12 genome as in Table 3.

  • c The pac gene is present inE. coli W.

  • d The substrates are thought to be arylsulfates because of the amino acid sequence similarities of the three gene products with known arylsulfatases.