TABLE 53.

Classification of proteins important for cell polarity developmenta

S. cerevisiae GOb termOrthologues found in Neurospora (homology over >60% of protein length)Domains conserved (e<-10)No matches found
Establishment of polarityABP1++, ACT1++, BCK1*, BEM1°, BNI1++, BUD6++, CDC3**, CDC10**, CDC11**, CDC12**, CDC24°, CDC42°, CKA1*, CKA2*, CKB1*, CKB2*, CLA4*, EXO70°°, EXO84°°, MLC1, PWP2, RGA1°, RGA2°, RHO1°, RHO2°, RHO3°, RHO4°, ROM1°, ROM2°, SEC3°°, SEC5°°, SEC6°°, SEC8°°, SEC10°°, SEC15°°, MYO2++, TPM1++, TPM2++BEM2°, BEM3°, BOI1, BOI2, CDC43, MSB1, SHS1**, SPA2°,BEM4°, GIC1°, GIC2°, PEA2°, LAS1, MSB2, SPH1°, SLG1°, ZDS1°, ZDS2°
ExocystEXO70°°, EXO84°°, SEC3°°, SEC5°°, SEC6°°, SEC8°°, SEC10°°, SEC15°°
PolarisomeBNI1++, BUD6++SPA2°PEA2°, SPH1°
Bud site selectionAXL1, BUD6, BUD7, BUD23, BUD31, BUD32, RSR1°, STE20*BUD10, BUD2°, BUD4, BUD5°, BUD13, BUD14, BUD20, RAX1, RAX2BUD3, BUD8, BUD9, BUD16, BUD17, BUD19, BUD22, BUD25, BUD26, BUD27, BUD28, BUD29, BUD30, HKR1, YOR300W
Axial buddingAXL1, CDC3**, CDC10**, CDC11**, CDC12**, ERV14°°, MYO1++, PFY1++, RSR1°BUD10, BNR1++, BUD2°, BUD4, BUD5°, ELM1*, GIN4°, KCC4°, PAN1++BUD3, GIC1°, GIC2°
Invasive growthCDC24°, CDC42°, RGA1°, RGA2°BEM3°, DIA3, DIA4, RIM20, SPT3+, STE12+DFG16, DIA1, DIA2, DIG1+, DIG2+, FLO8+, MUC1+, NRG1+, NRG2+, RIM8, RIM21, RXT2
Pseudohyphal growthBCY1*, BMH1, BMH2, CDC24°, CDC42°, CDC55*, DFG5, GPA2*, KSS1*, MEP2, PGU1, PLC1*, RAS2°, RGA1°, RGA2°, SHO1*, STE7*, STE11*, STE20*, TPK1*, TPK2*, TPK3*BEM3°, BUD5°, DFG10, DIA3, DIA4, ELM1*, FKH1+, FKH2+, PHD1+, SOK2+, SPA2°, STE12+ASH1+, BUD8, DIA1, ECM23, FLO8+, GPR1*, HMS1+, HMS2+, MSS11+, MUC1+, PAM1, TEC1+, SPH1°, SRO9°
  • a *, signaling components; **, septation machinery; °, Rho- and Ras-type GTPases modules and interacting proteins; °°, secretory pathway;+, transcriptional regulators;++, actin cytoskeleton.

  • b GO, gene ontology.