TABLE 44.

Heterotrimeric G-protein signaling, cAMP metabolism, and Ras proteins

Protein classNeurospora crassa proteinNCU no.BLAST match
Best overallS. cerevisiaeS. pombeAnimalaPlantb
Heterotrimeric GαGNA-106493.1Cryphonectria parasitica Cpg-1; 0.00Gpa2p; 1e-71Gpa1; 5e-70Gαi-3; e-102GPA1; 1e-48
GNA-206729.1Magnaporthe grisea MAGC; 1e-137Gpa2p; 3e-46Gpa1; 1e-59G-α65A; 3e-63GPA1; 2e-34
GNA-305206.1M. grisea MAGA; 1e-178Gpa2p; e-102Gpa2; 4e-85G-αi-3; e-102GPA1; 1e-48
Heterotrimeric GβGNB-100440.1M. grisea Gβ; 1e-164Ste4p; 5e-51Git5; 1e-60GPB-1; e-108Gβ; 2e-73
Heterotrimeric GγGNG-100041.1Botrytis cinerea CNS01BJB (Gγ); 9e-20NoneNoneNoneNone
Pheromone receptor (GPCR)PRE-100138.1Sordaria macrospora Pre-1; 1e-138Step3; 0.063NoneNoneNone
PRE-205758.1S. macrospora Pre2; 0.00NoneNoneNoneNone
Putative cAMP GPCRGPR-100786.1Dictyostelium discoideum CrlA; 3e-15NoneNoneNoneGPCR; 0.002
GPR-204626.1Arabidopsis thaliana GPCR CAA72145.1; 2e-09NoneNoneNoneGPCR; CAA72145.1; 2e-09
GPR-309427.1D. discoideum AA062367; 3e-07NoneNoneNoneGPCR CAA72145.1; 1e-04
Putative glucose sensor GPCRGPR-406312.1S. cerevisiae Gpr1p; 3e-14Gpr1p; 3e-14NoneNoneNone
Stm1-like GPCRGPR-500300.1S. cerevisiae YOL092w; 1e-29YOL092w; 1e-29Stm1; 1e-18NP_493686.1; 3e-13AT4g36850; 2e-14
GPR-609195.1S. cerevisiae YBR147w; 4e-32YBR147w; 4e-32Stm1; 8e-14Y43H11AL2; 2e-14NP_568009.1; 9e-10
Microbial opsinNOP-110055.1Leptosphaeria maculans opsin; 2e-75Yro2p; 1e-08SPCC31H12-02e; 9e-07NoneNone
Opsin-related proteinORP-101735.1Coriolus versicolor Hsp30; 5e-31Yro2p; 8e-23SPCC31H12.02c; 8e-12NoneNone
Phosducin00441.1C. parasitica Bdm-1; 2e-57NoneNoneNoneNone
00617.1S. cerevisiae Plp2p; 2e-42Plp2p; 2e-42SPBC2A9; 1e-34IAP-associated factor VIAF1; 8e-17F18O22.30; 9e-12
Regulator of G-protein signaling08319.1A. nidulans FlbA; e-139Sst2p; 1e-14C22F3.12c; 9e-27RGS16; 9e-05None
Adenylyl cyclaseCR-108377.1M. grisea MAC1; 0.00Cyr1p; 3e-160Adenylyl cyclase; e-111Scribbled; 1e-27F3M18.12; 1e-21
Cyclase-associated protein08008.1Candida albicans CAP; 2e-67Srv2p/CAP; 2e-65CAP; 1e-66CAP2; 1e-59Cap1; 1e-36
PKA regulatory subunitMCB01166.1Colletotricum lagenarium Rpk-1; e-142Bcy1p; 2e-67Cgs1; 2e-58PKA regulatory, type II α; 3e-55None
PKA catalytic subunit06240.1Colletotricum trifolii pkaC; e-164Tpk1p; e-129KapB; e-110PKA C-beta; 4e-93ATPK19; 2e-58
00682.1M. grisea PKA-ct; e-142Tpk1p; 5e-74KapB; 1e-67PKX1; 1e-81ATPK19; 2e-58
High-affinity cyclic nucleotide phosphodiesterase00478.1C. albicans high-affinity cAMP phospho- diesterase; 2e-45Pde2p; 4e-23NoneXP319716.1; 3e-25None
Low-affinity cyclic nucleotide phosphodiesterase00237.1S. pombe Pde1; 3e-16Pde1p; 4e-15Pde1; 3e-16NoneNone
RasRAS-108823.1Sclerotinia sclerotiorum hypothetical Ras; 3e-63Ras1p; 1e-24Ras1; 1e-26rRas2; 9e-28BAB78669.1; 1e-06
RAS-2/SMCO-703616.1U. maydis Ras2; 2e-57Ras2p; 2e-38CAA27399.1; 4e-39BAB27790.1; 2e-42Ric1; 9e-19
Ras-relatedKREV-102167.1H. sapiens Raichu404X; 6e-49Rsr1p; 3e-47CAA27399.1; 5e-33Raichu404X; 6e-49Ran1; 7e-18
  • a Caenorhabditis elegans, Drosophila melanogaster, Anopheles gambiae, Mus musculus, or Homo sapiens.

  • b Arabidopsis thaliana or Oryza sativa.