TABLE 18.

Nucleotide excision repair genes

S. cerevisiae geneFunctionNeurospora NCU no. (gene)ContigE valueBest match to Neurospora protein in SP + TrEMBLE value (BLASTP)
RAD15′ endonuclease07440.1 (mus-38)3.434e-140S. pombe Rad160.0
M. musculus XPFe-141
Human XPFe-140
S cerevisiae Rad1pe-134
RAD23′ endonuclease07498.1 (mus-40)3.4391e-72S. pombe Rad131e-87
S. cerevisiae Rad2p9e-68
Human XPG5e-55
RAD35′-3′ helicase01625.13.670.0S. pombe Rad150.0
S. cerevisiae Rad3p0.0
Human XPD0.0
RAD4GGR-specific damage recognition factor06585.13.3812e-28S. pombe Rad4 homologue2e-62
Drosophila MUS2105e-26
Human XPC8e-22
S. cerevisiae Rad4p3e-20
RAD7DNA damage recognition03649.13.1994e-11S. pombe Rad7 homologue2e-41
S. cerevisiae Rad7p4e-14
Human FBL63e-06
RAD105′ endonuclease07066.1 (mus-44)3.4138e-16S. pombe Swi103e-53
Rice Rad10 homologue2e-43
Human ERCC15e-42
S. cerevisiae Rad10p2e-13
RAD14Damaged DNA binding activity08742.1 (mus-43)3.5413e-34S. pombe Rad14 homologue1e-42
S. cerevisiae Rad14p4e-31
Human XPA3e-15
RAD16DNA damage recognition, DNA-dependent ATPase activity03650.13.1990.0S. cerevisiae Rad16p0.0
S. pombe Rhp160.0
Human Rad16 homologue2e-50
RAD23DNA damage recognition07542.13.4428e-31S. pombe Rad23 homologue9e-58
A. thaliana Rad23 homologue1e-39
Human HHR23B8e-32
Human HHR23A3e-21
S. cerevisiae Rad23p2e-29
RAD25/SSL2DNA helicase activity, TFIIH complex06438.13.3710.0S. pombe Rad25 homologue0.0
S. cerevisie Rad25p0.0
Human XPB0.0
RAD26DNA-dependent ATPase activity07837.13.4710.0S. pombe Rhp260.0
S. cerevisie Rad26p0.0
Human ERCC6/CSBe-154
RAD28UnknownNone
S. pombe uve1+UV damage-dependent endonuclease08850.1 (mus-18)3.5508e-99S. pombe Uve10.0
Bacillus UVSE1e-30
Human DDB1UV-damaged DNA binding protein06605.13.3821e-92O. sativa OSUVDDBe-122
A. thaliana AT4G05420e-108
Green monkey DDB17e-87
Human DDB12e-86