TABLE 2.

Proteins involved in cell wall biogenesis and cell division

Gene nameFunctionEC no.Present ina:
BFLWGLBAPBSGBBP
murB UDP-N-acetylmuramate dehydrogenase1.1.1.158+++++
murC UDP-N-acetylmuramate-l-alanine ligase6.3.2.8++++
murD UDP-N-acetylmuramoylalanine-d-glutamate ligase6.3.2.9+++++
murE UDP-N-acetylmuramoylalanyl-d-glutamate-2,6-diaminopimelate ligase6.3.2.13++++
ddlA d-Alanine-d-alanine ligase B6.3.2.4++++
murF UDP-N-acetylmuramoyl-tripeptide-d-alanyl-d-alanine ligase6.3.2.10++++
mraY Phospho-N-acetylmuramoylpentapeptide transferase2.7.8.13++++
murG UDP-N-acetylglucosamine--N-acetylmuramyl (pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase2.4.1.227+++++
amiB N-Acetylmuramoyl-l-alanine amidase3.5.1.28++++
nagA N-Acetylglucosamine-6-phosphate deacetylase3.5.1.25+
nagB Glucosamine-6-phosphate isomerase3.5.99.6+
glmU UDP-N-acetylglucosamine pyrophosphorylase2.7.7.23+++++
rodA Rod-shape-determining protein A
mreB Rod-shape-determining protein MreB++
mreC Rod-shape-determining protein MreC++
mreD Rod-shape-determining protein MreD++
mrdB Rod-shape-determining membrane protein; cell elongation in e phase++
mrdA Penicillin-binding protein 2++
mrcB Penicillin-binding protein 1b; peptidoglycan synthetase2.4.2-++++
uppS Undecaprenyl pyrophosphate synthetase2.5.1.31++++
mltA ++
mltC +
mltE Membrane-bound lytic murein transglycosylase E3.2.1.-+++
dapF Diaminopimelate epimerase+++++
minC Septum site-determining protein MinC+++++
minD Septum site-determining protein MinD+++++
minE Cell division topological specificity factor+++++
ftsY Cell division protein FtsY+++++
ftsW Cell division protein FtsW+++++
ftsA Cell division protein FtsA+++++
ftsQ Cell division protein FtsQ++
ftsZ Cell division protein FtsZ+++++
ftsL Cell division protein FtsL+++++
ftsI Penicillin-binding protein 3 precursor; peptidoglycan synthase2.4.1.129+++++
ftsJ Cell division protein FtsJ+++++
ftsH Cell division protein FtsH+++
ftsK Cell division protein FtsK++
mesJ Cell cycle protein MesJ+++++
  • a BFL, “Candidatus Blochmannia floridanus”; WGL, Wigglesworthia breviplapis; BAP, Buchnera from Acyrthosiphon pisum; BSG, Buchnera from Schizaphis graminum; BBP, Buchnera from Baizongia pistacea.