TABLE 1.

Genes that respond similarly to both glucose addition and Ras2 activationa

Induced genesRepressed genes
Protein biosynthesisbTranscriptionTransportcEnergy reserve metabolismdProtein turnoverStress response
RPS9A RPA43 NUP1 BCY1 PEP4 HSP30
RPS22B RPA49 NUP100 SDC25 RPN2 SSE2
RPS27A RPB5 NUP133 GAL83 RPN3 SSA3
RPL7B RPB9 NUP170 PHO85 RPN5 SSA4
RPL14B RPC40 MEX67 TPS1 RPN6 SSD1
RPL17B RPC82 RNA1 CIT3 RPN7 STO1
TIF11 RPO26 GSP1 GPD1 RPT1 CDC55
TIF3 RPO31 PSE1 MDH3 RPT3 UBC5
TIF34 RRP43 SXM1 PGM2 RPT4 PRE1
TEF4 RRP45 ALR21 HXT10 RPT5 PRE3
CDC60 RRP5 FET3 MRPL23 DOA1 GTS1
ARG8 ARG80 FET4 MRPL32 DOA4 CRS5
ARO7 BAS1 FKS1 PET112 APG13 CTA1
ARO8 DBP2 HNM1 PET117 APG14 GRX2
ASP1 DBP3 HXT2 PET191 APC9 TRX2
HIS1 GCR2 HXT4 PET54 HRD1 MDR1
HIS3 IFH1 LYP1 COQ1 HRD3 PAU1
ILS1 HMALPHA1 NPL3 COQ3 PEX14 PAU2
ILV1 IMP4 PHO84 COX10 MPD2 PAU3
LYS4 LEU3 ZRT1 COX11 SBA1 PPZ2
  • a See supplemental data associated with reference 408; a grand total of 758 genes exhibited a twofold or greater change in expression both within 20 min of glucose addition and within 20 min of the appearance of activated Ras2. Gene categories are based on Munich Information Center for Protein Sequences functional classification; a representative list from each category is shown. A total of 329 and 429 genes were in the induced and repressed categories, respectively.

  • b Includes genes encoding translational components (including ribosomal proteins), rRNA-processing factors, and amino acid biosynthetic enzymes.

  • c Includes genes encoding nucleocytoplasmic transport factors and plasma membrane transporters.

  • d Includes genes encoding factors involved in carbon storage and respiration (including mitochondrial factors).