TABLE 3.

Genes and operons in gram-positive bacteriaa containing functional cre's or being regulated by the P-Ser-HPr:CcpA complex

OrganismGene/operonFunctioncre sequencebCcpA effectcReference(s)
B. megateriumbamMβ-Amylase+48TGTTAACGCTTTCA+61457
B. megateriummbgAβ-Galactosidase−34TGATAAGGTTTTCA−21803
B. megateriummbgAβ-Galactosidase−21AGAAAACGTTATCA−8803
B. megateriumxylXylose metabolism+124TGAAAGCGCAAACA+137290
B. thuringiensiscry4ACry4A toxinNI399
C. perfringenscpeEnterotoxinNI+913
C. saccharobutylicumstaAStarch degradationNI162
E. faecalisbkdβ-Keto acid metabolismNI933
E. faecalisgalKETRGalactose metabolismNI453
E. faecalisgdh dhaKGlycerol dehydrogenase/dihydroxyacetone kinaseNI453
E. faecalis?Glucose starvation-induced proteinsNI453
E. faecalisldhLactate dehydrogenaseNI453
E. faecalispfkPhosphofructo kinaseNI453
E. faecalispykPyruvate kinaseNI453
E. faecalis?Serine dehydrataseNI453
L. caseinagN-AcetylglucosaminidaseNI568, 796
L. caseilacLactose metabolismNI568
L. delbrueckii subsp. bulgaricusccpACatabolism repressionNI574
L. delbrueckii subsp. lactispepQPeptidase−61TGCAATCGCTTACA−48+799
L. lactislasGlycolysisNI+494
L. lactisgalGalactose metabolismNI494
L. lactisptbA bglHβ-Glucoside metabolismNI569
L. lactisfruRCAFructose metabolismNI45
L. monocytogenes?β-GlucosidaseNI50
L. pentosusxpkAXylulose-5-P phosphoketolaseNI674
L. pentosusxylABXylose metabolismNI489
L. plantarumbglHP-β-glucosidase−3TGTAAGGGCTATCA+11511, 512
S. aureuspckAPEP carboxy kinaseNI791
S. bovisccpACcpA−68TGAAAAGGTTTTCA-54+27
S. bovisldhLactate dehydrogenaseNI27
S. bovispflPyruvate formate lyaseNI+27
S. gordoniiabpAAmylase bindingNI733
S. gordoniiarcAArginine deiminaseNI195
S. mutansfruAFructan hydrolase−164AGATAGCGCTTACA−15093, 946
S. mutansftfFructosyltransferaseNI+88
S. mutansgtfBCGlucosyltransferaseNI+88
S. pneumoniaecpsCapsular polysaccharideNI+273
S. rattusarcAArginine deiminaseNI298
S. thermophiluslacSZLactose metabolismNI897
S. thermophilusldhLactate dehydrogenaseNI897
S. xylosus?β-GlucoronideNI204
S. xylosusccpACatabolic repressorNI204
S. xylosuslacPHLactose metabolismNI46
S. xylosusmalMaltose metabolism−58TGCAAACGCTTGCA−45204
Consensus sequenceTGWNANCGNTNWCA939
  • a Except B. subtilis (for this organism, see references 178, 575, and 980).

  • b The numbers indicate the position with respect to the transcription initiation site. NI means not experimentally identified.

  • c CcpA acts either as catabolite activator (+) or as catabolite repressor (−).