TABLE 2.

Localization and functional classification of σ32 regulon productsa

Location or functional category (no. of products)Regulon products
Location
    Periplasm (8)CreAc, DsbCc, YceIc, YciMb, YehRe, YehZe, YgcIe, YibGe
    Inner membrane (27)CreCc, CutEc, CycAb, FtsHd, FxsAb,c,e, GntYc, HflXd, HflKd, HflCd, HtpXd, LipBc, LspAc, MacBb, MenAd, PgpAc, PhoQc, SdaCe, YafUe, YbeXc, YbeZb,c,e, YceJc, YcjFb,c, YciSb,c,e, YdgRe, YghJe, YiaAe, YtfLe
    Cytoplasm (88)ClpBd, ClpPd, ClpXd, CreBc, Crre, DnaJd, DnaKd, FkpBc, FimBe, FolPd, GapAd, GlnSc,e, GntXc,e, GroELSd, GrpEd, HepAc,e, Hfqc, HolCc,e, Hsp33c, HslUd, HslVd, HtpGd, IbpAd, IbpBd, IleSc,e, IspHc, LdhAb,e, Lond, MiaAd, Mfdb,e, Mlcd, MutLd, MutMb,c, NarPc,e, NrdHe, NusBc, PhoPc,e, PrlCb,c,e, PyrFc, RecAc, RecJc, RdgBc, RibEc, RluAb, RpmEe, RpoDd, RpsLe, RrmJd, rrnBd, SdaAc,e, ThiLc, TopAd, TreRe, TyrRc, ValSc, XerDc, YadFc,e, YafDc, YafEb,c, YbbNb,e, YbeDb,c,e, YbeYc, YbjXe, YccEe, YccVb,e, YcePb,c,e, YciHc, YcjXb,c,e, YdaMb, YdeOe, YdhQb,c,e, YeaDd, YfjNc, YfiAe, YgaDc, YgbFc, YggWc, YhdNc,e, YhiQb,c, YibAb,e, YjhIe, YjiTe, YnfKd, YrdAb,e, YrfHb,c, YrfGc,e, XapRe, ZntRc
Unknown (3)yi81_1d, yi82_1d, YpjMe
Functional category
    Metabolism (22)CutEc, FolPd, GapAd, IspHc, LdhAb,e, LipBc, LspAc, MenAd, NrdHe, PgpAc, PyrFc, RibEc, SdaAc,e, ThiLc, YadFc, YafEb,c, YceJc, YdaMb, YggWc, YibAb,e, YrdAb,e, YrfGc,e
    Chaperone/folding catalysts (12)ClpBd, DnaJd, DnaKd, DsbCc, FkpBc, GroELSd, GrpEd, Hsp33c, HtpGd, IbpAd, IbpBd, YbbNb,e
    Protein degradation (11)ClpPd, ClpXd, FtsHd, HflXd, HflKd, HflCd, HslUd, HslVd, HtpXd, Lond, PrlCb,c,e
    DNA modification (9)HolCc,e, Mfdb,e, MutLd, MutMb,c, RecAc, RecJc, RdgBc, TopAd, XerDc
    RNA state (3)Hfqd, RluAb, YfjNc
    Transcription regulators (18)CreBc, CreCc, CycAb, FimBe, HepAc,e, MacBb, Mlcd, NarPc,e, NusBc, PhoPc,e, PhoQc, RpoDd, TreRe, TyrRc, XapRe, YdeOe, YjhIe, ZntRc
    Translation/tRNA (11)GlnSc,e, IleSc,e, MiaAd, RpmEe, RpsLe, RrmJd, rrnBc, ValSc, YciHc, YfiAe, YrfHb,c
    Transporter (7)Crrc, GntXc,e, SdaCe, YbeXc, YbeZb,c,e, YdgRe, YehZe
    Miscellaneous (6)FxsAb,c,e, GntYc, YccVb,e, YhiQb,c, yi81_1d, yi82_1d
    Unknown function (27)CreAc, YafDc,e, YafUe, YbeDb,c,e, YbeYc, YbjXe, YccEe, YceIc,YcePb,c,e, YciMb,c, YciSb,c,e, YcjFb,c, YcjXb,c,e, YdhQb,c,e, YeaDd, YehRe, YgaDc, YgbFc, YgcIe, YghJe, YhdNc,e, YiaAe, YibGe, YjiTe, YnfKd, YpjMe, YtlLe
  • a The predicted functions (http://ecocyc.org) and locations (46) were obtained for all identified σ32 regulon products. Note that rrnB is an RNA. Underlined proteins are annotated as “membrane”; however, it is assumed that they are located in the inner membrane.

  • b Identified in reference 67.

  • c Identified in reference 43. Only regulon products encoded on the chromosome and with a confirmed σ32-dependent promoter are listed.

  • d Previously known; referred to in reference 43.

  • e Identified in reference 62.