TABLE 2.

HCH-degradative (lin) genes in HCH-degrading sphingomonadsa

GeneAmino acid residue(s)FunctionStrains (GenBank accession no.)
linA1/linA/linA2154/156DehydrochlorinaseUT26 (D90355), B90/B90A (AY331258, AY150580), Sp+ (AY903217, AY690622), DS2 (AJ871378), DS2-2 (AJ871379), γ1-7 (AJ871380), δ12-7 (AJ871381), γ16-1 (AJ871382), α1-2 (AJ871383), α4-2 (AJ871384), DS3-1 (AJ871385), BHC-A (DQ372106)
linB296Haloalkane dehalogenaseUT26 (D14594), B90A (AY331259), Sp+ (AY903216), BHC-A (DQ246619), MI1205 (AB278602), SS04-1 (AB304077), SS04-2 (AB304078), SS04-3 (AB304079), SS04-4 (AB304080), SS04-5 (AB304081)
linC250DehydrogenaseUT26 (D14595), B90A (AY331258), Sp+ (DQ111068), BHC-A (DQ462464)
linD346Reductive dechlorinaseUT26 (D89733), B90A (AY334273), BHC-A (DQ480725)
linE321Ring cleavage oxygenaseUT26 (AB021867), B90A (AY334273), BHC-A (DQ399709)
linR303LysR family transcriptional regulatorUT26 (AB021863), B90A (AY334273), BHC-A (DQ399711)
linF352Maleylacetate reductaseUT26 (AB177985), BHC-A (DQ399710)
linEb319Ring cleavage oxygenaseUT26 (AB177985)
linG156Acyl-CoA transferase
linH212Acyl-CoA transferase
linI267IclR family transcriptional regulator
linJ403Thiolase
linK316Putative ABC transporter system, inner membrane proteinUT26 (AB267475)
linL282Putative ABC transporter, ATPaseUT26 (AB267475)
linM320Putative ABC transporter system, periplasmic proteinUT26 (AB267475)
linN202Putative ABC transporter system, lipoproteinUT26 (AB267475)
linXb250DehydrogenaseUT26 (D23722), B90/B90A (AY331258, AY150580), BHC-A (DQ486136)
  • a Data from Nagata et al. (115), Kumari et al. (72), Dogra et al. (40), Böltner et al. (20), Cérémonie et al. (27), Lal et al. (75), Ito et al. (62), Nagata et al. (109), Wu et al. (191), and Yamamoto et al. (193).

  • b linX is apparently not required for the γ-HCH degradation pathway of S. japonicum UT26 (118).