TABLE 9.

Comparison of CRISPR-cas systems in bifidobacteria

SpeciesNo. of repeatsGroupaRepeat sequenceStructureb
B. longum subsp. longum DJO10A43ICAAGCTTATCAAGAAGGGTGAATGCTAATTCCCAGCc5-c1-c2-repeats
B. dentium Bd117ICAAGTTTATCAAGAAGGGTAGAAGCTAATTCCCAGTcsn1-c1-c2-repeats
81IIGTCGCTCTCCTCACGGAGAGCGTGGATTGAAATc3-c5-csd1-c1-repeats
B. dentium ATCC 2767815ICAAGTTTATCAAGAAGGGTAGAAGCTAATTCCCAGTc5-c1-c2-repeats
19IIGTCGCTCTCCTCACGGAGAGCGTGGATTGAAATc3-c5-csd1-csd2-c4-c1-c2-repeats
B. adolescentis ATCC 1570386IIGGTCGCTCTCCTTACGGAGAGCGTGGATTGAAATc3-c5-csd1a-csd1b-csd2-c4-c1-c2-repeats
B. adolescentis L2-32B113IIGGTCGCTCTCCTTACGGAGAGCGTGGATTGAAATc3-csd2-c4-c1-c2-repeats 2-repeats 1
B. animalis subsp. lactis AD01120IIICCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATc3-c_GSU0053-c1-repeats
B. animalis subsp. lactis HN01920IIICCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATc3-hyp-c_GSU0053-c2-c1-repeats
B. animalis subsp. lactis Bl-0422IIICCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATcsb3-c3-csb2-csb1-c2-c1-repeats
B. animalis subsp. lactis DSM 1014020IIICCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATcsb3-c3-csb2-csb1-c2-c1-repeats
B. animalis subsp. lactis Bb-1220IIICCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATcsb3-c3-csb2-csb1-hyp-c1-repeats
B. angulatum DSM 20098139?IVGTGTTCCCCGCACACGCGGGGATGATCCCc3-cse1-cse2-cse4-c5-cse3-c1-c2-repeats
B. catenulatum JCM119434IVGTGTTCCCCGCATACGCGGGGATGATCCCc3-truncated-cse4-c5-cse3-c1-c2-repeats
  • a CRISPR groups represent elements with identical repeat sequences.

  • b c1 to c5, CRISPR-associated cas1 to cas5 genes; csd1-csd2, CRISPR-associated csd1-csd2 family genes; c_GSU0053, GSU0053 family CRISPR-associated gene; cse1 to cse4, CRISPR-associated cse1 to cse4 family genes; csn1, CRISPR-associated csn1 family gene; hyp, hypothetical protein gene; truncated, incomplete draft sequence.