TABLE 2.

eSTPs in bacteriaa

SpecieseSTPTypePartner kinaseSubstrateFunctionPhospho-residue(s)MethodologyReference
Bacillus anthracisBa-Stp1PP2CBa-Stk1Ba-Stk1-PeSTKNAIn vitro phosphatase assay161
Bacillus subtilisPrpCPP2CPrkCEF-GTranslation factorNAIn vitro phosphatase assay50
CpGSmall ribosome-associated GTPaseNAIn vitro phosphatase assay1
EF-TuTranslation factorNAIn vitro phosphatase assay1
HPr kinasePhosphotransferase systemS46In vitro phosphatase assay169
PrkC-PeSTKNAIn vitro phosphatase assay129
YezBStress responseNAIn vitro phosphatase assay1
SpoIIEPPMSpoIIAAPhosphoprotein anti-anti-sigma factorNAIn vitro phosphatase assay127
RsbUPPMRsbV-PRsbV-PRegulation of sigma BNAIn vitro phosphatase assay193
RsbXPPMRsbS-PRsbSRegulation of sigma BNAIn vitro phosphatase assay193
Listeria monocytogenesStpPPMEF-TuTranslation factorNA2D phosphoprotein gel electrophoresis, in vitro phosphatase assay, decreased kirromycin sensitivity5
Mycobacterium tuberculosisPstPPPMPknBPBPAPBP, cell wallNAIn vitro phosphatase assay32
PknB-PeSTKT171/T173Mass spectrometry18
Mycoplasma pneumoniaePrpCPP2CHPrPhosphocarrier protein of phosphotransfer systemS46In vitro phosphatase assay61
Myxococcus xanthusPph1PP2CPkn5Pkn5Negative effector of developmentNAYeast two-hybrid interaction180
Staphylococcus aureusStp1PP2CStk1Stk1-PeSTKNAIn vitro phosphatase assay16
Streptococcus agalactiaeSaSTPPP2CPpaCFamily II inorganic pyrophosphataseIn vitro phosphatase assay144
PurAPurine biosynthesisNAIn vitro phosphatase assay
Streptococcus pneumoniaePhpPPP2CStkPStkP-PeSTKCoimmunoprecipitation131
RitRTranscriptional regulatorIn vitro phosphatase assay184
Streptococcus pyogenesSP-STPPP2CSP-STKSP-HLPHistone-like proteinThr(s)In vitro phosphatase assay72
Phospho-amino acid analysis
SP-STK-PeSTKNAIn vitro phosphatase assay72
  • a NA, not available.