Table 1

Major types and actions of cytokines

InterferonsRegulation of innate immunity, activation of antiviral properties, antiproliferative effects
InterleukinsGrowth and differentiation of leukocytes; many are proinflammatory
ChemokinesControl of chemotaxis, leukocyte recruitment; many are proinflammatory
Colony-stimulating factorsStimulation of hematopoietic progenitor cell proliferation and differentiation
Tumor necrosis factorProinflammatory, activates cytotoxic T lymphocytes