inflammatory

  • P2RX7 at the Host-Pathogen Interface of Infectious Diseases
    Review
    P2RX7 at the Host-Pathogen Interface of Infectious Diseases

    The P2X7 receptor (P2RX7) is an important molecule that functions as a danger sensor, detecting extracellular nucleotides from injured cells and thus signaling an inflammatory program to nearby cells. It is expressed in immune cells and plays important roles in pathogen surveillance and cell-mediated responses to infectious organisms.

    Alexandra Y. Soare, Tracey L. Freeman, Alice K. Min, Hagerah S. Malik, Elizabeth O. Osota, Talia H. Swartz
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