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microbiome

  • <em>Salmonella</em> versus the Microbiome
    Review
    Salmonella versus the Microbiome

    A balanced gut microbiota contributes to health, but the mechanisms maintaining homeostasis remain elusive. Microbiota assembly during infancy is governed by competition between species and by environmental factors, termed habitat filters, that determine the range of successful traits within the microbial community.

    Andrew W. L. Rogers, Renée M. Tsolis, Andreas J. Bäumler
  • Microbiota-Propelled T Helper 17 Cells in Inflammatory Diseases and Cancer
    Review
    Microbiota-Propelled T Helper 17 Cells in Inflammatory Diseases and Cancer

    Technologies allowing genetic sequencing of the human microbiome are opening new realms to discovery. The host microbiota substantially impacts immune responses both in immune-mediated inflammatory diseases (IMIDs) and in tumors affecting tissues beyond skin and mucosae. However, a mechanistic link between host microbiota and cancer or IMIDs has not been well established. Here, we propose T helper 17 (TH17) lymphocytes as the...

    Matteo Bellone, Arianna Brevi, Samuel Huber
  • Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection
    Review
    Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection

    The gut microbiome is critical in providing resistance against colonization by exogenous microorganisms. The mechanisms via which the gut microbiota provide colonization resistance (CR) have not been fully elucidated, but they include secretion of antimicrobial products, nutrient competition, support of gut barrier integrity, and bacteriophage deployment.

    Q. R. Ducarmon, R. D. Zwittink, B. V. H. Hornung, W. van Schaik, V. B. Young, E. J. Kuijper
  • Cross-Domain and Viral Interactions in the Microbiome
    Review
    Cross-Domain and Viral Interactions in the Microbiome

    The importance of the microbiome to human health is increasingly recognized and has become a major focus of recent research. However, much of the work has focused on a few aspects, particularly the bacterial component of the microbiome, most frequently in the gastrointestinal tract.

    Aislinn D. Rowan-Nash, Benjamin J. Korry, Eleftherios Mylonakis, Peter Belenky
  • Review
    The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota
    Christian Milani, Sabrina Duranti, Francesca Bottacini, Eoghan Casey, Francesca Turroni, Jennifer Mahony, Clara Belzer, Susana Delgado Palacio, Silvia Arboleya Montes, Leonardo Mancabelli, Gabriele Andrea Lugli, Juan Miguel Rodriguez, Lars Bode, Willem de Vos, Miguel Gueimonde, Abelardo Margolles, Douwe van Sinderen, Marco Ventura
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